Immunogen
Synthesized peptide derived from PIG-F . at AA range: 130-210
Specificity
PIG-F Polyclonal Antibody detects endogenous levels of PIG-F protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. The encoded protein and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],
Function
function:Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI.,pathway:Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.,similarity:Belongs to the PIGF family.,subunit:Forms a complex with PIGG and PIGO. PIGF is required to stabilize PIGG and PIGO.,
Protein name
Phosphatidylinositol-glycan biosynthesis class F protein
Other name
PIGF; Phosphatidylinositol-glycan biosynthesis class F protein; PIG-F; GPI11 homolog
Fields
>>Glycosylphosphatidylinositol (GPI)-anchor biosynthesis;>>Metabolic pathways
Human protein sequence Database
Q07326
Mouse protein sequence database
O09101
Rat protein sequence database
Cellular localization
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Tissue expression
Testis,
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