Molecular weight (DA)
20kD
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human CMTM6. AA range:131-180
Specificity
CMTM6 Polyclonal Antibody detects endogenous levels of CMTM6 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene is widely expressed in many tissues, but the exact function of the encoded protein is unknown. [provided by RefSeq, Jul 2008],
Function
similarity:Belongs to the chemokine-like factor family.,similarity:Contains 1 MARVEL domain.,tissue specificity:Expressed in the leukocytes, placenta and testis.,
Protein name
CKLF-like MARVEL transmembrane domain-containing protein 6
Other name
CMTM6; CKLFSF6; CKLF-like MARVEL transmembrane domain-containing protein 6; Chemokine-like factor superfamily member 6
Human protein sequence Database
Q9NX76
Mouse protein sequence database
Q9CZ69
Rat protein sequence database
Cellular localization
Cell membrane ; Multi-pass membrane protein . Early endosome membrane ; Multi-pass membrane protein . Recycling endosome membrane ; Multi-pass membrane protein . Co-localizes with PD-L1/CD274 in the plasma membrane and in recycling endosomes. .
Tissue expression
Expressed in the leukocytes, placenta and testis.
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