Molecular weight (DA)
22kD
Immunogen
The antiserum was produced against synthesized peptide derived from human DIRA1. AA range:149-198
Specificity
Di-Ras1 Polyclonal Antibody detects endogenous levels of Di-Ras1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
DIRAS1 belongs to a distinct branch of the functionally diverse Ras (see HRAS; MIM 190020) superfamily of monomeric GTPases.[supplied by OMIM, Apr 2004],
Function
function:Displays low GTPase activity and exist predominantly in the GTP-bound form.,similarity:Belongs to the small GTPase superfamily. Di-Ras family.,tissue specificity:Highly expressed in heart and brain.,
Protein name
GTP-binding protein Di-Ras1
Other name
DIRAS1; GBTS1; RIG; GTP-binding protein Di-Ras1; Distinct subgroup of the Ras family member 1; Ras-related inhibitor of cell growth; Rig; Small GTP-binding tumor suppressor 1
Human protein sequence Database
O95057
Mouse protein sequence database
Q91Z61
Rat protein sequence database
Cellular localization
Cell membrane ; Lipid-anchor ; Cytoplasmic side .
Tissue expression
Highly expressed in heart and brain.
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