Immunogen
The antiserum was produced against synthesized peptide derived from human GTPBP2. AA range:31-80
Specificity
GTPBP2 Polyclonal Antibody detects endogenous levels of GTPBP2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
GTP-binding proteins, or G proteins, constitute a superfamily capable of binding GTP or GDP. G proteins are activated by binding GTP and are inactivated by hydrolyzing GTP to GDP. This general mechanism enables G proteins to perform a wide range of biologic activities.[supplied by OMIM, Jan 2003],
Function
induction:Up-regulated by IFN-gamma in human monocytic cell line THP-1.,similarity:Belongs to the GTPBP1 GTP-binding protein family.,tissue specificity:Predominantly expressed in thymus, spleen, and testis. Expressed at lower levels in brain, lung, kidney, and ovary.,
Protein name
GTP-binding protein 2
Other name
GTPBP2; GTP-binding protein 2
Human protein sequence Database
Q9BX10
Mouse protein sequence database
Q3UJK4
Rat protein sequence database
Cellular localization
intracellular,intracellular membrane-bounded organelle,
Tissue expression
Predominantly expressed in thymus, spleen, and testis. Expressed at lower levels in brain, lung, kidney, and ovary.
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