Immunogen
The antiserum was produced against synthesized peptide derived from human GTPBP5. AA range:71-120
Specificity
GTPBP5 Polyclonal Antibody detects endogenous levels of GTPBP5 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Small G proteins, such as GTPBP5, act as molecular switches that play crucial roles in the regulation of fundamental cellular processes such as protein synthesis, nuclear transport, membrane trafficking, and signal transduction (Hirano et al., 2006 [PubMed 17054726]).[supplied by OMIM, Mar 2008],
Function
function:Involved in the ribosome maturation process. Plays a role of GTPase in vitro. When missing, mitochondria elongation and abnormal nuclear morphology are observed.,sequence caution:Translated as Gln.,similarity:Belongs to the GTP1/OBG family.,
Protein name
GTP-binding protein 5
Other name
GTPBP5; OBGH1; GTP-binding protein 5; Protein obg homolog 1; ObgH1
Human protein sequence Database
Q9H4K7
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Tissue expression
Muscle,Testis,
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