Molecular weight (DA)
41kD
Immunogen
The antiserum was produced against synthesized peptide derived from human Gz-alpha. AA range:1-50
Specificity
Gz-α Polyclonal Antibody detects endogenous levels of Gz-α protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
G protein subunit alpha z(GNAZ) Homo sapiens The protein encoded by this gene is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systms. This encoded protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids. [provided by RefSeq, Jul 2008],
Function
function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.,similarity:Belongs to the G-alpha family. G(i/o/t/z) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.,
Protein name
Guanine nucleotide-binding protein G(z) subunit alpha
Other name
GNAZ; Guanine nucleotide-binding protein G(z) subunit alpha; G(x) alpha chain; Gz-alpha
Fields
>>Long-term depression
Human protein sequence Database
P19086
Mouse protein sequence database
O70443
Rat protein sequence database
P19627
Cellular localization
Membrane; Lipid-anchor.
Tissue expression
Brain,PNS,
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