Molecular weight (DA)
36kD
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human CD300LG. AA range:41-90
Specificity
CD300g Polyclonal Antibody detects endogenous levels of CD300g protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Members of the CD300 (see MIM 606786)-like (CD300L) family, such as CD300LG, are widely expressed on hematopoietic cells. All CD300L proteins are type I cell surface glycoproteins that contain a single immunoglobulin (Ig) V-like domain (Takatsu et al., 2006 [PubMed 16876123]).[supplied by OMIM, Mar 2008],
Function
domain:Ig-like V-type domain mediates binding to lymphocyte.,function:Receptor which may mediate L-selectin-dependent lymphocyte rollings. Binds SELL in a calcium dependent manner. Binds lymphocyte.,PTM:O-glycosylated with sialylated oligosaccharides.,similarity:Belongs to the CD300 family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,tissue specificity:Highly expressed in heart, skeletal muscle and placenta.,
Protein name
CMRF35-like molecule 9
Other name
CD300LG; CLM9; TREM4; CMRF35-like molecule 9; CLM-9; CD300 antigen-like family member G; Triggering receptor expressed on myeloid cells 4; TREM-4; CD300g
Human protein sequence Database
Q6UXG3
Mouse protein sequence database
Q1ERP8
Rat protein sequence database
Cellular localization
Apical cell membrane ; Single-pass type I membrane protein . Basolateral cell membrane ; Single-pass type I membrane protein . Endosome, multivesicular body membrane ; Single-pass type I membrane protein . Transcytoses across the cytoplasm. .
Tissue expression
Highly expressed in heart, skeletal muscle and placenta.
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