Molecular weight (DA)
26kD
Immunogen
The antiserum was produced against synthesized peptide derived from human RAP2C. AA range:97-146
Specificity
Rap 2C Polyclonal Antibody detects endogenous levels of Rap 2C protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a member of the Ras-related protein subfamily of the Ras GTPase superfamily. Members of this family are small GTPases that act as molecular switches to regulate cellular proliferation, differentiation, and apoptosis. This protein has been reported to activate in vitro transcriptional activity of the serum response element. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012],
Function
similarity:Belongs to the small GTPase superfamily. Ras family.,tissue specificity:Expressed in mononuclear leukocytes and megakaryocytes. Not detected in platelets.,
Protein name
Ras-related protein Rap-2c
Other name
RAP2C; Ras-related protein Rap-2c
Human protein sequence Database
Q9Y3L5
Mouse protein sequence database
Q8BU31
Rat protein sequence database
Cellular localization
Cytoplasm . Recycling endosome membrane ; Lipid-anchor ; Cytoplasmic side .
Tissue expression
Expressed in liver, skeletal muscle, prostate, uterus, rectum, stomach, and bladder and to a lower extent in brain, kidney, pancreas, and bone marrow. Expressed in mononuclear leukocytes and megakaryocytes.
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