Molecular weight (DA)
150kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SOS2. AA range:631-680
Specificity
Sos 2 Polyclonal Antibody detects endogenous levels of Sos 2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a regulatory protein that is involved in the positive regulation of ras proteins. Mutations in this gene are associated with Noonan Syndrome-9. [provided by RefSeq, Jul 2016],
Function
function:Promotes the exchange of Ras-bound GDP by GTP.,online information:Son of sevenless entry,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 Ras-GEF domain.,
Protein name
Son of sevenless homolog 2
Other name
SOS2; Son of sevenless homolog 2; SOS-2
Fields
>>EGFR tyrosine kinase inhibitor resistance;>>Endocrine resistance;>>MAPK signaling pathway;>>ErbB signaling pathway;>>Ras signaling pathway;>>Chemokine signaling pathway;>>FoxO signaling pathway;>>Phospholipase D signaling pathway;>>mTOR signaling pathway;>>PI3K-Akt signaling pathway;>>Focal adhesion;>>Gap junction;>>JAK-STAT signaling pathway;>>Natural killer cell mediated cytotoxicity;>>T cell receptor signaling pathway;>>B cell receptor signaling pathway;>>Fc epsilon RI signaling pathway;>>Thermogenesis;>>Neurotrophin signaling pathway;>>Regulation of actin cytoskeleton;>>Insulin signaling pathway;>>GnRH signaling pathway;>>Estrogen signaling pathway;>>Prolactin signaling pathway;>>Relaxin signaling pathway;>>Growth hormone synthesis, secretion and action;>>Alcoholism;>>Hepatitis C;>>Hepatitis B;>>Human cytomegalovirus infection;>>Human papillomavirus infection;>>Pathways in cancer;>>Proteoglycans in cancer;>>MicroRNAs in cancer;>>Chemical carcinogenesis - receptor activation;>>Che
Human protein sequence Database
Q07890
Mouse protein sequence database
Q02384
Rat protein sequence database
Cellular localization
intracellular,cytosol,
Tissue expression
Brain,Placenta,
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车