Molecular weight (DA)
37kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SLC15A1. AA range:225-274
Specificity
PEPT1 Polyclonal Antibody detects endogenous levels of PEPT1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes an intestinal hydrogen peptide cotransporter that is a member of the solute carrier family 15. The encoded protein is localized to the brush border membrane of the intestinal epithelium and mediates the uptake of di- and tripeptides from the lumen into the enterocytes. This protein plays an important role in the uptake and digestion of dietary proteins. This protein also facilitates the absorption of numerous peptidomimetic drugs. [provided by RefSeq, Apr 2010],
Function
function:Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products.,similarity:Belongs to the PTR2/POT transporter (TC 2.A.17) family.,
Protein name
Solute carrier family 15 member 1
Other name
SLC15A1; PEPT1; Solute carrier family 15 member 1; Intestinal H(+)/peptide cotransporter; Oligopeptide transporter; small intestine isoform; Peptide transporter 1
Fields
>>Protein digestion and absorption
Human protein sequence Database
P46059
Mouse protein sequence database
Q9JIP7
Rat protein sequence database
P51574
Cellular localization
Membrane ; Multi-pass membrane protein .
Tissue expression
Intestine,PCR rescued clones,
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