Molecular weight (DA)
42kD
Immunogen
The antiserum was produced against synthesized peptide derived from human KCNK15. AA range:273-322
Specificity
TASK-5 Polyclonal Antibody detects endogenous levels of TASK-5 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
potassium two pore domain channel subfamily K member 15(KCNK15) Homo sapiens This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008],
Function
function:Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel.,polymorphism:Three variant polypeptides are known: TASK-5A, TASK-5B and TASK-5C. The sequence shown is that of TASK-5C.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Heterodimer .,tissue specificity:Detected in pancreas, heart, placenta, lung, liver, kidney, ovary, testis, skeletal muscle and adrenal gland, and at lower levels in prostate, spleen and thyroid gland.,
Protein name
Potassium channel subfamily K member 15
Other name
KCNK15; TASK5; Potassium channel subfamily K member 15; Acid-sensitive potassium channel protein TASK-5; TWIK-related acid-sensitive K(+) channel 5; Two pore potassium channel KT3.3; Two pore K(+) channel KT3.3
Human protein sequence Database
Q9H427
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Membrane; Multi-pass membrane protein.
Tissue expression
Detected in pancreas, heart, placenta, lung, liver, kidney, ovary, testis, skeletal muscle and adrenal gland, and at lower levels in prostate, spleen and thyroid gland.
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