Molecular weight (DA)
47kD
Immunogen
The antiserum was produced against synthesized peptide derived from human KCNK12. AA range:336-385
Specificity
THIK-2 Polyclonal Antibody detects endogenous levels of THIK-2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
potassium two pore domain channel subfamily K member 12(KCNK12) Homo sapiens This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008],
Function
function:Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Heterodimer .,
Protein name
Potassium channel subfamily K member 12
Other name
KCNK12; Potassium channel subfamily K member 12; Tandem pore domain halothane-inhibited potassium channel 2; THIK-2
Human protein sequence Database
Q9HB15
Mouse protein sequence database
Rat protein sequence database
Q9ERS1
Cellular localization
Membrane ; Multi-pass membrane protein .
Tissue expression
Epithelium,PNS,
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