Molecular weight (DA)
90kD
Immunogen
The antiserum was produced against synthesized peptide derived from human BRD3. AA range:611-660
Specificity
BRD3 Polyclonal Antibody detects endogenous levels of BRD3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known. [provided by RefSeq, Jul 2008],
Function
disease:A chromosomal aberration involving BRD3 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with NUT which produces a BRD3-NUT fusion protein.,similarity:Contains 2 bromo domains.,tissue specificity:Ubiquitous.,
Protein name
Bromodomain-containing protein 3
Other name
BRD3; KIAA0043; RING3L; Bromodomain-containing protein 3; RING3-like protein
Human protein sequence Database
Q15059
Mouse protein sequence database
Q8K2F0
Rat protein sequence database
Cellular localization
Nucleus . Detected on chromatin. .
Tissue expression
Ubiquitous.
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