Molecular weight (DA)
30kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SPIN1. AA range:111-160
Specificity
Spindlin-1 Polyclonal Antibody detects endogenous levels of Spindlin-1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:May play a role in cell-cycle regulation during the transition from gamete to embryo.,PTM:Phosphorylated during oocyte meiotic maturation.,sequence caution:Translated as Glu.,similarity:Belongs to the SPIN/STSY family.,
Function
function:May play a role in cell-cycle regulation during the transition from gamete to embryo.,PTM:Phosphorylated during oocyte meiotic maturation.,sequence caution:Translated as Glu.,similarity:Belongs to the SPIN/STSY family.,
Other name
SPIN1; OCR; SPIN; Spindlin-1; Ovarian cancer-related protein
Human protein sequence Database
Q9Y657
Mouse protein sequence database
Q61142
Rat protein sequence database
Q4V8J7
Cellular localization
Nucleus . Nucleus, nucleolus .
Tissue expression
Highly expressed in ovarian cancer tissues.
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