Molecular weight (DA)
37kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SPON2. AA range:71-120
Specificity
Mindin Polyclonal Antibody detects endogenous levels of Mindin protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Cell adhesion protein that promote adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens.,similarity:Contains 1 spondin domain.,similarity:Contains 1 TSP type-1 domain.,tissue specificity:Expressed in normal lung tissues but not in lung carcinoma cell lines.,
Function
function:Cell adhesion protein that promote adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens.,similarity:Contains 1 spondin domain.,similarity:Contains 1 TSP type-1 domain.,tissue specificity:Expressed in normal lung tissues but not in lung carcinoma cell lines.,
Other name
SPON2; DIL1; Spondin-2; Differentially expressed in cancerous and non-cancerous lung cells 1; DIL-1; Mindin
Human protein sequence Database
Q9BUD6
Mouse protein sequence database
Q8BMS2
Rat protein sequence database
Q9WV75
Cellular localization
Secreted, extracellular space, extracellular matrix .
Tissue expression
Expressed in normal lung tissue but not in lung carcinoma cell lines.
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