Immunogen
Synthesized peptide derived from human C-ternal S43A3
Specificity
This antibody detects endogenous levels of S43A3 at Human, Mouse
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 IHC 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobases such as adenine, guanine and hypoxanthine . May regulate fatty acid (FA) transport in adipocytes, acting as a positive regulator of FA efflux and as a negative regulator of FA uptake (By similarity). ; [Isoform 1]: Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine . Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane . ; [Isoform 2]: Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine . Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane .
Gene Name
SLC43A3 PSEC0252
Protein name
Solute carrier family 43 member 3 (Protein FOAP-13)
Other name
Solute carrier family 43 member 3 (Protein FOAP-13)
Human protein sequence Database
Q8NBI5
Mouse protein sequence database
A2AVZ9
Rat protein sequence database
Cellular localization
Basolateral cell membrane ; Multi-pass membrane protein .
Tissue expression
Widely expressed with highest levels in the liver and lung, followed by the pancreas (PubMed:26455426). Highly expressed in macrophages (Ref.1).
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