Immunogen
Synthesized peptide derived from human N-ternal WNT2B
Specificity
This antibody detects endogenous levels of WNT2B at Human, Mouse
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 IHC 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Plays a redundant role in embryonic lung development.
Protein name
Protein Wnt-2b (Protein Wnt-13)
Other name
Protein Wnt-2b (Protein Wnt-13)
Human protein sequence Database
Q93097
Mouse protein sequence database
O70283
Rat protein sequence database
Cellular localization
Secreted, extracellular space, extracellular matrix . Secreted .
Tissue expression
Isoform 1 is expressed in adult heart, brain, placenta, lung, prostate, testis, ovary, small intestine and colon. In the adult brain, it is mainly found in the caudate nucleus, subthalamic nucleus and thalamus. Also detected in fetal brain, lung and kidney. Isoform 2 is expressed in fetal brain, fetal lung, fetal kidney, caudate nucleus, testis and cancer cell lines.
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