Molecular weight (DA)
94kD
Immunogen
SynSynthesized peptide derived from human RHBDF2thesized peptide derived from human RHBDF2
Specificity
This antibody detects endogenous levels of RHBDF2 at Human, Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, and 0.1157% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Function
Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.
Gene Name
RHBDF2 IRHOM2 RHBDL5 RHBDL6
Protein name
Inactive rhomboid protein 2 (iRhom2) (Rhomboid 5 homolog 2) (Rhomboid family member 2) (Rhomboid veinlet-like protein 5) (Rhomboid veinlet-like protein 6)
Human protein sequence Database
Q6PJF5
Mouse protein sequence database
Q80WQ6
Rat protein sequence database
Cellular localization
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cell membrane .
Tissue expression
Found in the epidermis and esophageal epithelium.
Storage
‘-15°C to -25°C/1 year(Do not lower than -25°C)
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