Molecular weight (DA)
37kD
Immunogen
Synthesized peptide derived from human TRMT10A
Specificity
This antibody detects endogenous levels of TRMT10A at Human, Mouse,Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Function
S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in tRNAs . Probably not able to catalyze formation of N(1)-methyladenine at position 9 (m1A9) in tRNAs .
Gene Name
TRMT10A RG9MTD2
Protein name
tRNA methyltransferase 10 homolog A (EC 2.1.1.-) (RNA (guanine-9-)-methyltransferase domain-containing protein 2)
Human protein sequence Database
Q8TBZ6
Mouse protein sequence database
Q8C1Z8
Rat protein sequence database
Q4KLI2
Cellular localization
Nucleus . Nucleus, nucleolus .
Tissue expression
Expressed in embryonic and fetal brain. It is expressed throughout the dorsal telencephalon at 8 and 11 weeks of gestation, with highest expression in ventricular zone and marginal zone. Detected in cerebellar cortex and nuclei, but not in dorsal telencephalon, at later stages.
Storage
‘-15°C to -25°C/1 year(Do not lower than -25°C)
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