Immunogen
A synthesized peptide derived from Human CD32
Dilution rate
FC: 5μL per test for million cells or whole blood in 100 μL volume.
Purification process (Immunogen)
Background
CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).
Other name
Fc fragment of IgG; low affinity IIb; receptor (CD32); CD32; FCG2; CD32B; FCGR2; IGFR2
Human gene ID
SwissProt ID
P31994
Human protein sequence Database
Gene ID
2213
Mouse protein sequence database
Rat protein sequence database
Storage
Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles.