Molecular weight (DA)
Molecular Weight
Calculated MW: 44 kDa; Observed MW: 28 kDa
Immunogen
A synthetic peptide of human SIRT3
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100
Purification process (Immunogen)
Background
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.
Human gene ID
SwissProt ID
Q9NTG7
Human protein sequence Database
Gene ID
23410
Mouse protein sequence database
Rat protein sequence database
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.