Molecular weight (DA)
Molecular Weight
Calculated MW: 44 kDa; Observed MW: 53 kDa
Immunogen
A synthesized peptide derived from human TXNIP
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100
Purification process (Immunogen)
Background
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm.
Other name
HHCPA78; THIF; TXNIP; VDUP1
Human gene ID
SwissProt ID
Q9H3M7
Human protein sequence Database
Gene ID
10628
Mouse protein sequence database
Rat protein sequence database
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.