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Phospho-TrkB (Tyr817) Rabbit mAb

Refer to | for labeled antibodies

Specification

BYab-17882

  • 50UL $180 100UL $255
  • Delivery: In Stock

Product introduction Experimental scheme Citation Related products

Product introduction>

Host
Reactiveness
Use
Molecular weight (DA)
Molecular Weight Calculated MW: 92 kDa; Observed MW: 140 kDa
Immunogen
A synthesized peptide derived from human Phospho-TrkB (Y817)
Specificity
Source
Formulation
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/30
Purification process (Immunogen)
Concentration
Background
The family of Trk receptor tyrosine kinases consists of TrkA, TrkB and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3. TrkA regulates proliferation and is important for development and maturation of the nervous system. Point mutations, deletions and chromosomal rearrangements (chimeras) cause ligand-independent receptor dimerization and activation of TrkA.
Function
Gene Name
NTRK2
Protein name
Abbreviation
Other name
NTRK2; TRKB; BDNF/NT-3 growth factors receptor; GP145-TrkB; Trk-B; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase; Tropomyosin-related kinase B
Fields
Human gene ID
SwissProt ID Q16620
Human protein sequence Database
Gene ID 4915
Mouse gene ID
Mouse protein sequence database
Rat gene ID
Rat protein sequence database
Cellular localization
Tissue expression
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Experimental scheme>

Procedure

Citation>

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Phospho-TrkB (Tyr817) Rabbit mAb

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