Molecular weight (DA)
Molecular Weight
Calculated MW: 80 kDa; Observed MW: 90 kDa
Immunogen
A synthesized peptide derived from human PSD95
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
Purification process (Immunogen)
Background
Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons.
Other name
DLG4; Disks large homolog 4; PSD95; SAP90; Synapse associated protein 90
Human gene ID
SwissProt ID
P78352
Human protein sequence Database
Gene ID
1742
Mouse protein sequence database
Rat protein sequence database
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.