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HDAC6 (3B2) Mouse mAb

Refer to | for labeled antibodies

Specification

BYab-17909

  • 50UL $180 100UL $255
  • Delivery: In Stock

Product introduction Experimental scheme Citation Related products

Product introduction>

Host
Reactiveness
Use
Molecular weight (DA)
Molecular Weight Calculated MW: 131 kDa; Observed MW: 160 kDa
Immunogen
Purified recombinant human HDAC6 protein expressed in E.coli.
Specificity
Source
Formulation
Dilution rate
WB: 1/500-1/1000
Purification process (Immunogen)
Concentration
Background
Involved in the regulation of many cellular processes, including cell migration, immune synapse formation, viral infection, and degradation of misfolded proteins. HDAC6 binds to both poly-ubiquitinated misfolded proteins and dynein motors, facilitating the transport of misfolded proteins to the aggresome. Required for subsequent recruitment of the autophagic machinery and clearance of aggresomes from the cell. Plays a key role in the protection against the deleterious effects of pathological protein aggregation that occurs in various diseases.
Function
Gene Name
HDAC6
Protein name
Abbreviation
Other name
HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6
Fields
Human gene ID
SwissProt ID Q9UBN7
Human protein sequence Database
Gene ID 10013
Mouse gene ID
Mouse protein sequence database
Rat gene ID
Rat protein sequence database
Cellular localization
Tissue expression
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Experimental scheme>

Procedure

Citation>

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HDAC6 (3B2) Mouse mAb

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