Molecular weight (DA)
63kD
Immunogen
Synthesized peptide derived from human SLC40A1. AA range 1-100
Specificity
This antibody detects endogenous levels of SLC40A1 at Human, Mouse,Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Function
Major iron transporter that plays a key role in balancing cellular and systemic iron levels . Transports iron from intestinal, splenic, and hepatic cells into the blood to provide iron to other tissues (By similarity). Controls therefore dietary iron uptake, iron recycling by macrophages, and release of iron stores in hepatocytes (By similarity). When iron is in excess, hepcidin/HAMP levels increase resulting in a degradation of ferroportin/SLC40A1 limiting the iron efflux to plasma .
Gene Name
SLC40A1 FPN1 IREG1 SLC11A3 MSTP079
Protein name
Solute carrier family 40 member 1 (Ferroportin-1) (Iron-regulated transporter 1)
Human protein sequence Database
Q9NP59
Mouse protein sequence database
Q9JHI9
Rat protein sequence database
Q923U9
Cellular localization
Cell membrane ; Multi-pass membrane protein . Localized to the basolateral membrane of polarized epithelial cells.
Tissue expression
Detected in erythrocytes (at protein level). Expressed in placenta, intestine, muscle and spleen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车