Molecular weight (DA)
93kD
Immunogen
Synthesized peptide derived from human AXIN2
Specificity
This antibody detects endogenous levels of AXIN2 at Human, Mouse,Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Function
Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B.
Protein name
Axin-2 (Axin-like protein) (Axil) (Axis inhibition protein 2) (Conductin)
Human protein sequence Database
Q9Y2T1
Mouse protein sequence database
O88566
Rat protein sequence database
O70240
Cellular localization
Cytoplasm .
Tissue expression
Expressed in brain and lymphoblast.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)