Molecular weight (DA)
57kD
Immunogen
Synthesized peptide derived from human Perilipin-1
Specificity
This antibody detects endogenous levels of Perilipin-1 at Human, Mouse,Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Function
Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels.
Gene Name
PLIN1 PERI PLIN
Protein name
Perilipin-1 (Lipid droplet-associated protein)
Human protein sequence Database
O60240
Mouse protein sequence database
Q8CGN5
Rat protein sequence database
P43884
Cellular localization
Endoplasmic reticulum . Lipid droplet . Lipid droplet surface-associated. .
Tissue expression
Detected in adipocytes from white adipose tissue (at protein level) (PubMed:27832861). Detected in visceral adipose tissue and mammary gland (PubMed:9521880).
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
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