Molecular weight (DA)
52kD
Immunogen
Synthesized peptide derived from human SELENBP1
Specificity
This antibody detects endogenous levels of SELENBP1 at Human, Mouse,Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Function
Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria . Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport (By similarity).
Protein name
Selenium-binding protein 1 (56 kDa selenium-binding protein) (SBP56) (SP56)
Human protein sequence Database
Q13228
Mouse protein sequence database
P17563
Rat protein sequence database
Q8VIF7
Cellular localization
Nucleus . Cytoplasm, cytosol . Membrane ; Peripheral membrane protein . May associate with Golgi membrane (By similarity). May associate with the membrane of autophagosomes (By similarity). .
Tissue expression
Widely expressed. Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
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