Molecular weight (DA)
28kD
Immunogen
Synthesized peptide derived from human C4BPB
Specificity
This antibody detects endogenous levels of C4BPB at Human,Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Function
Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.
Protein name
C4b-binding protein beta chain
Human protein sequence Database
P20851
Mouse protein sequence database
Rat protein sequence database
Q63515
Cellular localization
Secreted.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)