Molecular weight (DA)
21kD
Immunogen
Synthesized peptide derived from human RHOC
Specificity
This antibody detects endogenous levels of RHOC at Human, Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azid
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Function
Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells.
Protein name
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Human protein sequence Database
P08134
Mouse protein sequence database
Q62159
Rat protein sequence database
Cellular localization
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cleavage furrow . Translocates to the equatorial region before furrow formation in a ECT2-dependent manner.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
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