Immunogen
Synthesized peptide derived from NY-CO-8 . at AA range: 520-600
Specificity
NY-CO-8 Polyclonal Antibody detects endogenous levels of NY-CO-8 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a centrosome associated protein. This protein may be involved in organizing the centrosome during interphase and mitosis. Mutations in this gene are associated with retinal-renal ciliopathy. [provided by RefSeq, Oct 2010],
Function
subunit:Homodimer.,tissue specificity:Expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors.,
Protein name
Serologically defined colon cancer antigen 8
Other name
SDCCAG8; CCCAP; NPHP10; HSPC085; Serologically defined colon cancer antigen 8; Antigen NY-CO-8; Centrosomal colon cancer autoantigen protein; hCCCAP
Human protein sequence Database
Q86SQ7
Mouse protein sequence database
Q80UF4
Rat protein sequence database
Cellular localization
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, cilium basal body . Cell junction. Located at the distal ends of both centrioles and colocalizes to centrosomes throughout the cell cycle.; [Isoform 2]: Cytoplasm.
Tissue expression
Expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors.
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