Molecular weight (DA)
52kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SERC3. AA range:361-410
Specificity
TDE1 Polyclonal Antibody detects endogenous levels of TDE1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:May be involved in cellular transformation.,PTM:N-glycosylated.,similarity:Belongs to the TDE1 family.,tissue specificity:Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.,
Function
function:May be involved in cellular transformation.,PTM:N-glycosylated.,similarity:Belongs to the TDE1 family.,tissue specificity:Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.,
Protein name
Serine incorporator 3
Other name
SERINC3; DIFF33; TDE1; SBBI99; Serine incorporator 3; Tumor differentially expressed protein 1
Fields
>>Viral life cycle - HIV-1
Human protein sequence Database
Q13530
Mouse protein sequence database
Q9QZI9
Rat protein sequence database
Cellular localization
Cell membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein .; Cytoplasm, perinuclear region . (Microbial infection) Upon HIV-1 infection, it is redirected to perinuclear region following interaction with HIV-1 Nef, excluding it from virions particles, thereby preventing subsequent antiviral defense activity (Probable). .
Tissue expression
Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.
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