Immunogen
The antiserum was produced against synthesized peptide derived from human ABCA13. AA range:2251-2300
Specificity
ABCA13 Polyclonal Antibody detects endogenous levels of ABCA13 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
In human, the ATP-binding cassette (ABC) family of transmembrane transporters has at least 48 genes and 7 gene subfamilies. This gene is a member of ABC gene subfamily A (ABCA). Genes within the ABCA family typically encode several thousand amino acids. Like other ABC transmembrane transporter proteins, this protein has 12 or more transmembrane alpha-helix domains that likely arrange to form a single central chamber with multiple substrate binding sites. It is also predicted to have two large extracellular domains and two nucleotide binding domains as is typical for ABCA proteins. Alternative splice variants have been described but their biological validity has not been demonstrated.[provided by RefSeq, Mar 2009],
Function
sequence caution:Translated as Glu.,similarity:Belongs to the ABC transporter family.,similarity:Contains 2 ABC transporter domains.,tissue specificity:Expressed in testis, bone marrow and trachea.,
Protein name
ATP-binding cassette sub-family A member 13
Other name
ABCA13; ATP-binding cassette sub-family A member 13
Fields
>>ABC transporters
Human protein sequence Database
Q86UQ4
Mouse protein sequence database
Q5SSE9
Rat protein sequence database
Cellular localization
Cytoplasmic vesicle membrane ; Multi-pass membrane protein .
Tissue expression
Significantly expressed in the bone marrow, trachea, testis, thyroid and lung as well as in skin fibroblasts.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车