Molecular weight (DA)
43kD
Immunogen
The antiserum was produced against synthesized peptide derived from human Fra-1. AA range:101-150
Specificity
Fra-1 Polyclonal Antibody detects endogenous levels of Fra-1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],
Function
similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. Fos subfamily.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer.,
Protein name
Fos-related antigen 1
Other name
FOSL1; FRA1; Fos-related antigen 1; FRA-1
Fields
>>Wnt signaling pathway;>>Osteoclast differentiation;>>IL-17 signaling pathway;>>Human T-cell leukemia virus 1 infection
Human protein sequence Database
P15407
Mouse protein sequence database
P48755
Rat protein sequence database
P10158
Cellular localization
Nucleus .
Tissue expression
Blood,Endothelial cell,Kidney,Skin,
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车