Molecular weight (DA)
38kD
Immunogen
The antiserum was produced against synthesized peptide derived from human JunD. AA range:222-271
Specificity
Jun D Polyclonal Antibody detects endogenous levels of Jun D protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. Immunoprecipitation: 2-5 ug/mg lysate. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216). [provided by RefSeq, Nov 2013],
Function
function:Binds an AP-1 site and upon cotransfection stimulates the activity of a promoter that bears an AP-1 site.,similarity:Belongs to the bZIP family. Jun subfamily.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer.,
Protein name
Transcription factor jun-D
Other name
JUND; Transcription factor jun-D
Fields
>>MAPK signaling pathway;>>Osteoclast differentiation;>>IL-17 signaling pathway;>>Parathyroid hormone synthesis, secretion and action
Human protein sequence Database
P17535
Mouse protein sequence database
P15066
Rat protein sequence database
P52909
Cellular localization
Nucleus.
Tissue expression
Epithelium,Spleen,
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