Molecular weight (DA)
40kD
Immunogen
The antiserum was produced against synthesized peptide derived from human ZC3H8. AA range:81-130
Specificity
Fliz1 Polyclonal Antibody detects endogenous levels of Fliz1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 3 C3H1-type zinc fingers.,
Function
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 3 C3H1-type zinc fingers.,
Protein name
Zinc finger CCCH domain-containing protein 8
Other name
ZC3H8; ZC3HDC8; Zinc finger CCCH domain-containing protein 8
Human protein sequence Database
Q8N5P1
Mouse protein sequence database
Q9JJ48
Rat protein sequence database
Cellular localization
Nucleus . Colocalizes with coilin in subnuclear cajal and histone locus bodies. Translocates in the LEC complex to cajal and histone locus bodies at snRNA genes in a ICE1-dependent manner. Associates to transcriptionally active chromatin at snRNA genes.
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