Molecular weight (DA)
29kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SPIC. AA range:131-180
Specificity
Spi-C Polyclonal Antibody detects endogenous levels of Spi-C protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene regulates the development of red pulp macrophages, which are necessary for iron homeostasis and the recycling of red blood cells. [provided by RefSeq, Aug 2016],
Function
function:Probable transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,subunit:Binds DNA as a monomer.,tissue specificity:Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver.,
Protein name
Transcription factor Spi-C
Other name
SPIC; Transcription factor Spi-C
Human protein sequence Database
Q8N5J4
Mouse protein sequence database
Q6P3D7
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver.
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