Molecular weight (DA)
134kD
Immunogen
The antiserum was produced against synthesized peptide derived from human CEP135. AA range:1081-1130
Specificity
CEP135 Polyclonal Antibody detects endogenous levels of CEP135 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
centrosomal protein 135(CEP135) Homo sapiens This gene encodes a centrosomal protein, which acts as a scaffolding protein during early centriole biogenesis, and is also required for centriole-centriole cohesion during interphase. Mutations in this gene are associated with autosomal recessive primary microcephaly-8. [provided by RefSeq, Jun 2012],
Function
similarity:Belongs to the CEP135/TSGA10 family.,
Protein name
Centrosomal protein of 135 kDa
Other name
CEP135; CEP4; KIAA0635; Centrosomal protein of 135 kDa; Cep135; Centrosomal protein 4
Human protein sequence Database
Q66GS9
Mouse protein sequence database
Q6P5D4
Rat protein sequence database
Cellular localization
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . During centriole biogenesis, it is concentrated within the proximal lumen of both parental centrioles and procentrioles.
Tissue expression
Brain,Epithelium,Placenta,
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