Molecular weight (DA)
74kD
Immunogen
The antiserum was produced against synthesized peptide derived from human CEP76. AA range:251-300
Specificity
CEP76 Polyclonal Antibody detects endogenous levels of CEP76 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a centrosomal protein which regulates centriole amplification by limiting centriole duplication to once per cell cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012],
Function
regulation of cell cycle process, regulation of centrosome duplication, regulation of microtubule-based process,regulation of organelle organization, regulation of centriole replication, regulation of centrosome cycle, regulation of cytoskeleton organization, regulation of cell cycle, regulation of microtubule cytoskeleton organization,
Protein name
Centrosomal protein of 76 kDa
Other name
CEP76; C18orf9; Centrosomal protein of 76 kDa; Cep76
Human protein sequence Database
Q8TAP6
Mouse protein sequence database
Q0VEJ0
Rat protein sequence database
Cellular localization
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Does not localize along the ciliary axoneme.
Tissue expression
Brain,Stomach,Teratocarcinoma,
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