Molecular weight (DA)
24kD
Immunogen
The antiserum was produced against synthesized peptide derived from human TCTP. AA range:71-120
Specificity
HRF Polyclonal Antibody detects endogenous levels of HRF protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Involved in calcium binding and microtubule stabilization.,similarity:Belongs to the TCTP family.,subunit:Interacts with STEAP3.,tissue specificity:Found in several healthy and tumoral cells including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, and lymphomas. It cannot be detected in kidney and renal cell carcinoma (RCC). Expressed in placenta and prostate.,
Function
function:Involved in calcium binding and microtubule stabilization.,similarity:Belongs to the TCTP family.,subunit:Interacts with STEAP3.,tissue specificity:Found in several healthy and tumoral cells including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, and lymphomas. It cannot be detected in kidney and renal cell carcinoma (RCC). Expressed in placenta and prostate.,
Protein name
Translationally-controlled tumor protein
Other name
TPT1; Translationally-controlled tumor protein; TCTP; Fortilin; Histamine-releasing factor; HRF; p23
Human protein sequence Database
P13693
Mouse protein sequence database
P63028
Rat protein sequence database
P63029
Cellular localization
Cytoplasm .
Tissue expression
Found in several healthy and tumoral cells including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, and lymphomas. It cannot be detected in kidney and renal cell carcinoma (RCC). Expressed in placenta and prostate.
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