Molecular weight (DA)
38kD
Immunogen
Synthesized peptide derived from MRP-L3 . at AA range: 20-100
Specificity
MRP-L3 Polyclonal Antibody detects endogenous levels of MRP-L3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L3P ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 13q. [provided by RefSeq, Jul 2008],
Function
similarity:Belongs to the ribosomal protein L3P family.,
Protein name
39S ribosomal protein L3 mitochondrial
Other name
MRPL3; MRL3; RPML3; 39S ribosomal protein L3; mitochondrial; L3mt; MRP-L3
Human protein sequence Database
P09001
Mouse protein sequence database
Q99N95
Rat protein sequence database
Cellular localization
Mitochondrion .
Tissue expression
Cervix,
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