Molecular weight (DA)
30kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
CLC1A Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The encoded protein may play a role in regulating dendritic cell function. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
Function
similarity:Contains 1 C-type lectin domain.,tissue specificity:Expressed preferentially in dendritic cells.,
Gene Name
CLEC1A CLEC1 UNQ569/PRO1131
Protein name
C-type lectin domain family 1 member A (C-type lectin-like receptor 1) (CLEC-1)
Human protein sequence Database
Q8NC01
Mouse protein sequence database
Q8BWY2
Rat protein sequence database
Cellular localization
Membrane ; Single-pass type II membrane protein .
Tissue expression
Expressed preferentially in dendritic cells.
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