Molecular weight (DA)
24kD
Immunogen
The antiserum was produced against synthesized peptide derived from human MRPS7. AA range:91-140
Specificity
MRP-S7 Polyclonal Antibody detects endogenous levels of MRP-S7 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. In the prokaryotic ribosome, the comparable protein is thought to play an essential role in organizing the 3' domain of the 16 S rRNA in the vicinity of the P- and A-sites. Pseudogenes corresponding to
Function
similarity:Belongs to the ribosomal protein S7P family.,subunit:Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.,
Protein name
28S ribosomal protein S7 mitochondrial
Other name
MRPS7; 28S ribosomal protein S7; mitochondrial; MRP-S7; S7mt; bMRP-27a; bMRP27a
Human protein sequence Database
Q9Y2R9
Mouse protein sequence database
Q80X85
Rat protein sequence database
Q5I0K8
Cellular localization
Mitochondrion .
Tissue expression
Eye,Skeletal muscle,Small intestine,Umbilical cord blood,
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