Molecular weight (DA)
40kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SERPINB9. AA range:241-290
Specificity
PI-9 Polyclonal Antibody detects endogenous levels of PI-9 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Mar 2012],
Function
function:Granzyme B inhibitor.,similarity:Belongs to the serpin family.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,
Other name
SERPINB9; PI9; Serpin B9; Cytoplasmic antiproteinase 3; CAP-3; CAP3; Peptidase inhibitor 9; PI-9
Human protein sequence Database
P50453
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cytoplasm.
Tissue expression
Bone marrow,Human esophagus tumor,Placenta,Testis,
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