Molecular weight (DA)
46kD
Immunogen
The antiserum was produced against synthesized peptide derived from human RPL3. AA range:211-260
Specificity
Ribosomal Protein L3 Polyclonal Antibody detects endogenous levels of Ribosomal Protein L3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Ribosomes, the complexes that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L3P family of ribosomal proteins and it is located in the cytoplasm. The protein can bind to the HIV-1 TAR mRNA, and it has been suggested that the protein contributes to tat-mediated transactivation. This gene is co-transcribed with several small nucleolar RNA genes, which are located in several of this gene's introns. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul
Function
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:The L3 protein is a component of the large subunit of cytoplasmic ribosomes.,similarity:Belongs to the ribosomal protein L3P family.,
Protein name
60S ribosomal protein L3
Abbreviation
Ribosomal Protein L3
Other name
RPL3; OK/SW-cl.32; 60S ribosomal protein L3; HIV-1 TAR RNA-binding protein B; TARBP-B
Fields
>>Ribosome;>>Coronavirus disease - COVID-19
Human protein sequence Database
P39023
Mouse protein sequence database
P27659
Rat protein sequence database
P21531
Cellular localization
Nucleus, nucleolus . Cytoplasm .
Tissue expression
Brain,Colon,Colon adenocarcinoma,Lung,Muscle,Ovary,PNS,Prostate,Skeletal muscle,Ski
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