Molecular weight (DA)
75 100kD
Immunogen
Synthesized peptide derived from human ADAM 12 (Cleaved-Glu208)
Specificity
This antibody detects endogenous levels of Human,Mouse ADAM 12 (Cleaved-Glu208, protein was cleaved amino acid sequence between 207-208)
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Gene Name
ADAM12 MLTN UNQ346/PRO545
Protein name
ADAM 12 (Cleaved-Glu208)
Other name
Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12;EC 3.4.24.-;Meltrin-alpha)
Human protein sequence Database
O43184
Mouse protein sequence database
Q61824
Rat protein sequence database
Cellular localization
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.; [Isoform 3]: Secreted .; [Isoform 4]: Secreted .
Tissue expression
Isoform 1 is expressed in placenta and skeletal, cardiac, and smooth muscle. Isoform 2 seems to be expressed only in placenta or in embryo and fetus. Both forms were expressed in some tumor cells lines. Not detected in brain, lung, liver, kidney or pancreas.
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