Molecular weight (DA)
54kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 320-400
Specificity
TRI35 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified. [provided by RefSeq, Jul 2008],
Function
domain:The RING finger domain and the coiled-coil region are required for the apoptosis-inducing activity.,function:May play a role as a tumor suppressor. Implicated in the cell death mechanism.,similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 B box-type zinc finger.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 RING-type zinc finger.,subcellular location:Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies.,
Gene Name
TRIM35 HLS5 KIAA1098
Protein name
Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5)
Human protein sequence Database
Q9UPQ4
Mouse protein sequence database
Q8C006
Rat protein sequence database
Q5RKG6
Cellular localization
Cytoplasm . Nucleus . Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies (By similarity). .
Tissue expression
Brain,Liver,Lung,
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