Molecular weight (DA)
19kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 40-120
Specificity
ARF5 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
ADP ribosylation factor 5(ARF5) Homo sapiens This gene is a member of the human ADP-ribosylation factor (ARF) gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6). The members of each class share a common gene organization. [provided by RefSeq, Dec 2010],
Function
function:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.,similarity:Belongs to the small GTPase superfamily.,similarity:Belongs to the small GTPase superfamily. Arf family.,subunit:Binds ASAP2.,
Protein name
ADP-ribosylation factor 5
Human protein sequence Database
P84085
Mouse protein sequence database
P84084
Rat protein sequence database
P84083
Cellular localization
Golgi apparatus . Cytoplasm, perinuclear region . Membrane ; Lipid-anchor . Golgi apparatus, trans-Golgi network membrane ; Lipid-anchor .
Tissue expression
Brain,Lung,Skin,Tongue,
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