Molecular weight (DA)
65kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 340-420
Specificity
ARSJ Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Sulfatases (EC 3.1.5.6), such as ARSJ, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules (Sardiello et al., 2005 [PubMed 16174644]).[supplied by OMIM, Mar 2008],
Function
cofactor:Binds 1 calcium ion per subunit.,PTM:The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.,similarity:Belongs to the sulfatase family.,
Gene Name
ARSJ UNQ372/PRO708
Protein name
Arylsulfatase J (ASJ) (EC 3.1.6.-)
Human protein sequence Database
Q5FYB0
Mouse protein sequence database
Q8BM89
Rat protein sequence database
Cellular localization
Secreted .
Tissue expression
Chondrosarcoma,Human lung,Skin,
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